Mitochondrial calcium signaling is crucial for energy metabolism and calcium homeostasis, but monitoring it accurately is challenging due to pH fluctuations. Existing GECIs are often sensitive to pH ...

Mitochondrial calcium signalling plays a fundamental role in cellular homeostasis by modulating energy production and activating key metabolic enzymes. Calcium ions (Ca2+) are dynamically exchanged ...

Northwestern Medicine scientists have discovered how calcium signaling channels in microglia—the primary immune cells of the brain—regulate neuroinflammation and promote the development of behaviors ...

Cerebral blood delivery depends on mechanisms such as electrical signaling, which propagates through capillary networks to upstream arterioles to deliver blood, and calcium signaling, which fine-tunes ...

Calcium signalling represents a fundamental process in cellular communication, orchestrating diverse physiological responses from muscle contraction to neurotransmission and gene regulation. At the ...

Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be ...

A new method exposes key details of the mechanism behind calcium signaling in prokaryotes for the first time. Working in a Listeria monocytogenes model, researchers from Umeå University (Sweden) led ...

Left: A blue light pulse of 0.1 seconds triggers a calcium signal (red) in guard cells, which is followed by an anion current (black). Right: The influx of calcium into the cell promotes the release ...

Researchers discover that skin can activate the immune system and enhance vaccines, paving the way for more potent and ...

Plant pests such as bacteria and fungi lead to significant yield losses in agriculture. In order to develop new strategies against such pathogens, understanding the plant's immune response is of ...