Scientists show DNA polymerases can build long, patterned DNA without a template, opening new paths for synthetic biology and ...
Researchers discovered a kinase-driven phosphorylation switch that activates DNA packaging machinery, aligning nucleosomes at ...
The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...
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DNA-copying enzymes caught making errors that could reshape DNA writing
Researchers at the University of Bristol have caught DNA-copying enzymes generating long stretches of genetic code without ...
A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...
DNA replication is a complex process with many moving parts. In baker's yeast, the molecular complex Ctf18-RFC keeps parts of the replication machinery from falling off the DNA strand. Human cells use ...
When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting that involves construction of spindles to carefully separate the DNA after ...
Scientists reveal a hidden second layer of human DNA, showing how genome folding controls genes and influences disease development.
Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists ...
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