Dynamic switching between revival stem cells and conventional intestinal stem cells enables efficient tissue repair without ...

Attrition in the therapeutic pipeline is often linked to the gap in translational efficacy between the pre-clinical phase and clinical outcomes. Organoids offer strong potential for improving disease ...

Attrition in the therapeutic pipeline can often be associated with the lack of translational efficacy from the pre-clinical phase to the clinic. Organoids demonstrate the significant potential to ...

A team led by Prof. Dr. Dirk Haller has demonstrated for the first time that defective mitochondria cause injuries in the intestinal epithelium and influence the microbiome. In this microscopic image ...

The trillions of microbes in our gastrointestinal tract, known as the gut microbiome, are crucial to the body; the gut microbiome aids in digestion, nutrient absorption, and influences our health in ...

Ebola virus and Marburg virus are both highly contagious filoviruses and are among the most lethal viruses known. Patient deaths are often a consequence of gastrointestinal damage leading to diarrhea ...

Organoids are three-dimensional, miniaturized, and simplified versions of organs produced in vitro from stem cells or organ-specific progenitor cells. They recapitulate key structural and functional ...