RMD Open

Transformative improvement with staggered gains in rheumatoid arthritis remission and sustained remission, but higher relapse rates: a population-based cohort study …

Objectives To report population-level data describing long-term trends in remission, sustained remission and relapse among ...
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RMD Open

is an open access, peer reviewed rheumatology journal that publishes original research on musculoskeletal disorders and rheumatic conditions ...
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Time to diagnosis in large vessel vasculitis: insights from a retrospective study at a tertiary rheumatology centre

Objective To evaluate the diagnostic pathway of patients affected by large vessel vasculitis (LVV) and to determine factors associated with the time to diagnosis including referring and previously ...
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Site-specific articular responses to b/tsDMARDs in rheumatoid arthritis: a longitudinal observational study from the Swiss Clinical Quality Management Registry

Objectives Whether treatment response differs across affected joints in rheumatoid arthritis (RA) remains unclear. We sought to determine whether responses to tumour necrosis factor inhibitors (TNFi) ...
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A phase III, randomised, double-blind, multi-dose, placebo- and naproxen-controlled study to evaluate the efficacy and safety of fasinumab in patients with pain due to ...

Background Chronic pain due to osteoarthritis (OA) causes considerable burden, and current treatment options are limited. This phase III study aimed to compare the efficacy and safety of fasinumab, an ...
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Efficacy of risankizumab across GRAPPA domains in psoriatic arthritis: a pooled analysis of patients from the phase 3 KEEPsAKE 1 and 2 studies

Objective To assess the efficacy of long-term treatment with risankizumab across the updated Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) domains and key related ...
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Outcomes of patients with systemic lupus erythematosus treated with belimumab: a post hoc efficacy analysis of five phase III clinical trials by British Isles Lupus Assessment ...

Objectives To determine belimumab efficacy assessed using the British Isles Lupus Assessment Group (BILAG)-based Combined Lupus Assessment (BICLA) in patients with systemic lupus erythematosus (SLE) ...
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Continued nintedanib in patients with systemic sclerosis-associated interstitial lung disease: 3-year data from SENSCIS-ON

Objective We assessed adverse events and changes in forced vital capacity (FVC) in patients treated with open-label nintedanib over 148 weeks of SENSCIS-ON, the extension of the SENSCIS trial. Methods ...
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Systemic disease activity measured with ESSDAI varies largely over 5 years in a prospective, longitudinal cohort of patients with Sjögren’s disease

Objectives The objectives are to evaluate variation in systemic disease activity (European Alliance of Associations For Rheumatology (EULAR) Sjögren’s Syndrome Disease Activity Index (ESSDAI)) over ...
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Predictive value of myositis antibodies: role of semiquantitative classification and positivity for more than one autoantibody

Objectives We assessed the positive predictive value (PPV) of 17 myositis antibodies for having a diagnosis of myositis and other myositis-spectrum conditions (interstitial lung disease (ILD), ...
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Artificial intelligence in rheumatology research: what is it good for?

Artificial intelligence (AI) is transforming rheumatology research, with a myriad of studies aiming to improve diagnosis, prognosis and treatment prediction, while also showing potential capability to ...
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Chronic kidney disease in patients with psoriatic arthritis: a cohort study

Objectives Chronic kidney disease (CKD) is a comorbidity in psoriatic arthritis (PsA). We aimed to define the prevalence of CKD in patients with PsA, describe their long-term renal outcomes and ...